Can Endogenous Neuromodulation meet our society’s most critical needs?

Between January 2023 and December 2024, inpatient mental health claims increased by 80% in the US, while outpatient claims increased by 40%. This indexes a mental health crisis in our country of unprecedented scope. Here’s the context: Our national health status is worse than that of our peer countries, and it is declining in all age brackets. Our life expectancy is ranked lowest, as is our infant mortality rate (by a factor of two with respect to the average of our peers). This trend has been long underway. Back in 1991, the book titled “Betrayal of Health” was published that identified the usual culprits in our looming healthcare crisis: Personal behavior, nutrition-less food, toxics in the environment and in our agriculture, etc. A ‘biobehavioral’ remedy was urgently called for.

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A Case of Chemical Injury and PTSD
by Carolyn McLuskie, MA, RCC and Siegfried Othmer, Ph.D.

When someone comes for neurofeedback with severe symptoms, we are not likely to be confronted with a single, narrowly definable issue. In cases of chemical injury that significantly compromise health and functionality going forward, the issue is inherently complex because it quite naturally evokes a trauma response as well. The dearth of available remedies makes for dim prospects. And if that occurs in a person with a history of early emotional trauma, this additional ongoing trauma is a compounding factor on what is already a problematic presentation.

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by Carolyn McLuskie, MA, RCC and Siegfried Othmer, Ph.D.

An Open Letter to Mark A. Reger, Department of Veterans Affairs

Eugene Peniston

Dear Dr. Reger:

I just read your article in JAMA with great interest. I would like to draw your attention to a recent publication on a controlled study of neuromodulation in application to treatment-resistant PTSD that was completed recently at the VA Pacific Islands Health Care System in Honolulu. It recruited 87 participants. This was a study of Endogenous Neuromodulation, a second-generation neurofeedback in which the brain is simply engaging with its real-time dynamics in the EEG and Infra-Low Frequency domains. This method has its roots in the early EEG neurofeedback, and thus has been under development for nearly forty years.

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Enhancing the effectiveness of neurofeedback for dementia and cognitive impairments through corrective doses of ascorbic acid.

Neurofeedback has established itself as a safe and effective technique that can enhance brain function–through improving the efficiency of the neural networks in the brain. It has proven its effectiveness in disorders such as epilepsy, ADHD, head injuries, learning disabilities, autism, mood instabilities, sleep and chronic pain. In such cases we are dealing with a reasonably healthy neural network that is not in an optimal state of functioning. By “healthy”, I mean in terms of the physical integrity of the overall neural structure –where the issue is confined to the domain of network timing and sequencing. In this regard, neurofeedback has been very successful in restoring, or at least improving, overall functionality in the brain by challenging the mechanisms of neural network regulation. With respect to issues of state regulation, these mechanisms are predominantly sub-cortical.

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A Revisionist View of Neurofeedback

One reason that formal research on neurofeedback by people in the academic community hasn’t generally matched what is being accomplished clinically is surely that researchers tended to take the operant conditioning model seriously. Plainly, the rigorous instantiation of a ‘purist’ operant conditioning design of the original SMR-beta protocols leads to a rather inefficient training procedure. This can also be said of the original work of Sterman and Lubar, as they were doing their utmost to stay true to B.F. Skinner’s experimental design. Their work sufficed to provide the method a rigorous and sound foundation, but in the clinical realm such an inefficient method of brain training would be dead on arrival.

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Research with Infra-Low Frequency Neurofeedback

ILF Neurofeedback Mechanisms and Neurophysiology

Othmer, S., and Othmer, S.F. (2024) Endogenous Neuromodulation at Infra-Low Frequency: Method and Theory, DOI: 10.20944/preprints202310.1085.v2
https://www.researchgate.net/publication/374784708_Endogenous_Neuromodulation_at_Infra-Low_Frequency_Method_and_Theory

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